Cannabis, a cause for anxiety? A critical appraisal of the anxiogenic and anxiolytic properties. · PMID 33008420

Sharpe L, Sinclair J, Kramer A, de Manincor M, Sarris J.

Study design: Systematic review
Population / model: Human · Animal
Published: 2020-10-02
Journal: Journal of translational medicine

From the author abstract

“Acute doses of CBD were found to reduce anxiety both in animals and humans, without having an anxiogenic effect at higher doses. …”

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Figures from the paper

Fig. 1: Summary of biphasic anxiolytic/anxiogenic effects of cannabis — **Fig. 1** Summary of biphasic anxiolytic/anxiogenic effects of cannabisSharpe L, Sinclair J, Kramer A, de Manincor M, Sarris J. Journal of translational medicine (2020). Original figure · CC BY · Resized for display.

Fig. 2: Process of identification and screening of articles for inclusion — **Fig. 2** Process of identification and screening of articles for inclusionSharpe L, Sinclair J, Kramer A, de Manincor M, Sarris J. Journal of translational medicine (2020). Original figure · CC BY · Resized for display.

Citation and indexing details

PMID 33008420 · PMC7531079

Publication types: Journal Article; Research Support, Non-U.S. Gov't; Systematic Review

Topic tags: Anxiety & stress

Metadata checked 2026-11-04. Study design and model tags follow indexing and explicit abstract terms. Citation counts are not evidence of benefit. An available full text does not by itself permit image reuse.