Effectiveness of THC-containing cannabis for inflammatory bowel disease: a systematic review. · PMID 42231518

THC Cannabis formulations

Jugl S, Perez-Vilar S, Galati S, Sandhu SK, Chen HK, Chang SH, Wang Y, Kurzbach T, Adkins L, Guo J, Wang Y, Winterstein AG, Goodin A.

Study design: Systematic review
Population / model: Not indexed
Published: 2026-06-03
Journal: Journal of cannabis research

From the author abstract

“Four randomized clinical trials (RCTs), and four non-interventional studies met all inclusion criteria. Non-interventional studies exhibited serious or critical risk of bias, …”

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Figures from the paper

Fig. 1: Flowchart of studies included in the systematic review. Study selection flow diagram for the systematic review, detailing records identified in four databases ( — **Fig. 1** Flowchart of studies included in the systematic review. Study selection flow diagram for the systematic review, detailing records identified in four databases (n = 885), abstract screened (n = 583), assessed for eligibility (n = 69), and reasons for exclusion. Eight studies met inclusion criteria and were retained for risk of bias assessmentJugl S, Perez-Vilar S, Galati S, Sandhu SK, Chen HK, Chang SH, Wang Y, Kurzbach T, Adkins L, Guo J, Wang Y, Winterstein AG, Goodin A. Journal of cannabis research (2026). Original figure · CC BY · Resized for display.

Fig. 2: Risk of bias assessment for randomized controlled trials. Risk of bias assessment of the four randomized controlled trials included in this review, using the Co — **Fig. 2** Risk of bias assessment for randomized controlled trials. Risk of bias assessment of the four randomized controlled trials included in this review, using the Cochrane RoB 2.0 tool across domains D1–D5 and overall judgement. Green circles indicate low risk of bias, yellow circles some concerns, and red circles high risk of biasJugl S, Perez-Vilar S, Galati S, Sandhu SK, Chen HK, Chang SH, Wang Y, Kurzbach T, Adkins L, Guo J, Wang Y, Winterstein AG, Goodin A. Journal of cannabis research (2026). Original figure · CC BY · Resized for display.

Citation and indexing details

PMID 42231518 · PMC13455333

Publication types: Journal Article; Systematic Review

Topic tags: Inflammation & immunity

Metadata checked 2026-11-04. Study design and model tags follow indexing and explicit abstract terms. Citation counts are not evidence of benefit. An available full text does not by itself permit image reuse.