Lavender IG, Marshall NS, McCartney D, Cho G, Irwin C, Suraev A, Gordon R, Arnold JC, D'Rozario AL, Gordon CJ, Saini B, Sivam S, Zheng Y, Grunstein RR, Yee BJ, McGregor IS, Hoyos CM.
- Study design
- Randomized trial
- Population / model
- Human
- Published
- 2026-02-16
- Journal
- Journal of sleep research
Reviewed study note
What this study reported
The primary wake-after-sleep-onset outcome was not significantly changed; some secondary measures differed and adverse events were recorded.
- Population
- 20 adults with physician-diagnosed insomnia disorder.
- Studied preparation
- Defined oral CBN preparations compared with matched placebo.
- Interpretation limit
- Single-night arms and a small sample do not establish sustained benefit, broad safety or equivalence to retail sleep products.
From the author abstract
“Larger, longer trials are warranted.”
A short attributed excerpt. Read the full abstract and original paper for methods, results and limitations.
Outcome summaries · provisional
Selected source sets; evidence confidence remains ungraded.
Citation and indexing details
PMID 41698831 · PMC13357646
Publication types: Journal Article; Randomized Controlled Trial
Topic tags: Sleep
Metadata checked 2026-11-04. Study design and model tags follow indexing and explicit abstract terms. Citation counts are not evidence of benefit. An available full text does not by itself permit image reuse.