Receptor mechanisms · CBD, CBG, CBC, CBDA, THC, THCA
Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8
The Journal of pharmacology and experimental therapeutics · PMID 18354058
Cell and isolated-neuron assays
- Studied preparation
- Individual phytocannabinoids tested in defined channel assays.
- Population / model
- Engineered HEK-293 cells and isolated rat sensory neurons.
- What was observed
- The experiments measured channel-related calcium responses under laboratory conditions.
Mechanistic cell activity does not establish human symptom relief; concentrations and test systems do not map directly onto a bottle.
Online publication · Source checked 2026-10-25
Sources, registration and terms
Citation and publication date recorded; peer-review/preprint status not separately classified.
No full-text link recorded here; a DOI does not promise free full text.
No registration recorded for this paper; this is not a claim that none exists.
CBD / cannabidiol · CBG / cannabigerol · CBC / cannabichromene · Acidic cannabinoids: CBDA / THCA · THC / delta-9 THC · In vitro